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020 _a9783540787655
_9978-3-540-78765-5
024 7 _a10.1007/978-3-540-78765-5
_2doi
050 4 _aQH505
072 7 _aPHVN
_2bicssc
072 7 _aSCI009000
_2bisacsh
072 7 _aPHVN
_2thema
072 7 _aPHVD
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082 0 4 _a571.4
_223
245 1 0 _aAspects of Physical Biology
_h[electronic resource] :
_bBiological Water, Protein Solutions, Transport and Replication /
_cedited by G. Franzese, M. Rubi.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2008.
300 _aIX, 233 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aLecture Notes in Physics,
_x0075-8450 ;
_v752
505 0 _aBiological Water -- Dynamics of Water at Low Temperatures and Implications for Biomolecules -- Anomalous Behaviour of Supercooled Water and Its Implication for Protein Dynamics -- Interactions of Polarizable Media inWater and the Hydrophobic Interaction -- Protein and Biological Solutions -- Metastable Mesoscopic Phases in Concentrated Protein Solutions -- Application of Discrete Molecular Dynamics to Protein Folding and Aggregation -- Cooperative Effects in Biological Suspensions: From Filaments to Propellers -- Transport and Replication -- A Thermodynamic Description of Active Transport -- Energy Interconversion in Transport ATPases Role of Water in Ions Transport and in the Energy of Hydrolysis of Phosphate Compounds -- A Novel Mechanism for Activator-Controlled Initiation of DNA Replication that Resolves the Auto-regulation Sequestration Paradox -- Activity-Dependent Model for Neuronal Avalanches.
520 _aThe application to Biology of the methodologies developed in Physics is attracting an increasing interest from the scientific community. It has led to the emergence of a new interdisciplinary field, called Physical Biology, with the aim of reaching a better understanding of the biological mechanisms at molecular and cellular levels. Statistical Mechanics in particular plays an important role in the development of this new field. For this reason, the XXth session of the famous Sitges Conference on Statistical Physics was dedicated to "Physical Biology: from Molecular Interactions to Cellular Behavior". As is by now tradition, a number of lectures were subsequently selected, expanded and updated for publication as lecture notes, so as to provide both a state-of-the-art introduction and overview to a number of subjects of broader interest and to favor the interchange and cross-fertilization of ideas between biologists and physicists. The present volume focuses on three main subtopics (biological water, protein solutions as well as transport and replication), presenting for each of the them the on-going debates on recent results. The role of water in biological processes, the mechanisms of protein folding, the phases and cooperative effects in biological solutions, the thermodynamic description of replication, transport and neural activity, all are subjects that are revised in this volume, based on new experiments and new theoretical interpretations.
650 0 _aStatistical physics.
650 1 4 _aBiological and Medical Physics, Biophysics.
_0http://scigraph.springernature.com/things/product-market-codes/P27008
650 2 4 _aComplex Systems.
_0http://scigraph.springernature.com/things/product-market-codes/P33000
650 2 4 _aSoft and Granular Matter, Complex Fluids and Microfluidics.
_0http://scigraph.springernature.com/things/product-market-codes/P25021
650 2 4 _aStatistical Physics and Dynamical Systems.
_0http://scigraph.springernature.com/things/product-market-codes/P19090
700 1 _aFranzese, G.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aRubi, M.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783642097577
776 0 8 _iPrinted edition:
_z9783540871323
776 0 8 _iPrinted edition:
_z9783540787648
830 0 _aLecture Notes in Physics,
_x0075-8450 ;
_v752
856 4 0 _uhttps://doi.org/10.1007/978-3-540-78765-5
912 _aZDB-2-PHA
912 _aZDB-2-LNP
999 _c11606
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